| Probiotics
in Intestinal Disorders
Irritable Bowel Syndrome (IBS)
Studies have shown that an imbalance in the intestinal microflora
(“dysbiosis”)
may be an important factor in the development of symptoms for
some individuals with IBS. For example, the composition of the
intestinal microflora may affect the ability of the colon to
contract and relax.
Inflammatory Bowel Disease (IBD)
There is growing evidence that intestinal microflora play an
important role in the development of IBD. Experts believe that
manipulation of the intestinal microflora may be important in
helping to manage ulcerative colitis and pouchitis.
Bacterial Infections
Bifidobacteria produce substances such as bacteriocins, peroxides,
organic acids such as lactic acid and acetic acid, thus reducing
the intestinal pH, that may result in antagonizing the growth of
certain microorganisms ( such as E. coli, Staphylococcus aureus,
Salmonella, Schigella and yeast), and therefore helping the normal
function of the intestinal flora.
Studies also suggest that the regular ingestion of Lactobacillus-containing
probiotics may have an effect on Helicobacter pylori
that may cause stomach or intestinal ulcers and stomach cancer.
Constipation
Probiotics in the colon can convert undigested carbohydrates to short-chain
fatty acids, which reduces the pH of the colon that will result in an
increase in stool volume and weight, thereby helping with regular
bowel movements.
Diarrhea
Probiotics have been shown to reduce antibiotic-associated diarrhea
and children's acute infectious diarrhea such as rotavirus diarrhea.
Allergies
Probiotics may affect the production of inflammation-producing cells,
impact gut barrier function, regulate the secretion of inflammatory
mediators, and help promote the proper development of the
immune system. |